- Zytokine
- EP 0661933*WO 94/03075
- EP 0661987*WO 94/06449
- EP 0652953*WO 94/03600
- EP 0665739*WO 94/06399
- EP 0672064*WO 94/10203
- EP 0680334*WO 94/06420
- EP 0706563*WO 95/01434
- EP 0702566*WO 94/26307
- EP 0702560*WO 94/26293
- EP 0 662 146*WO 94/05800
- EP 0702695*WO 94/28016
- EP 0667870*WO 94/10187
- EP 0667784*WO 93/09800
- EP 0666912*WO 94/09134
- EP 0666756*WO 94/06455
- EP 0666868*WO 94/10202
- EP 0664700*WO 94/08574
- EP 0669829*WO 94/09803
- EP 0667872*WO 94/11402
- EP 0667903*WO 94/02611
- EP 0672133*WO 93/00567
- EP 0654998*WO 93/05788
- EP 0672061*WO 93/10151
- EP 0651656*WO 94/01133
- EP 0705107*WO 94/28926
- EP 0702566*WO 94/26307
- EP 0699236*WO 94/26891
- EP 0667899*WO 93/05148
- EP 0673420*WO 94/13801
- EP 0672144*WO 94/09138
- EP 0672145*WO 94/12638
- EP 0662976*WO 94/06818
- EP 0670733*WO 95/09004
- EP 0720483*WO 95/08345
- EP 0717849*WO 95/07467
- EP 0716609*WO 95/05191
- EP 0716610*WO 95/05846
- EP 0730647*WO 95/14778
- EP 0732944*WO 95/11045
- EP 0738329*WO 95/13393
- EP 0741783*WO 95/18856
- Peptide und Immunomodulatoren
- EP 0733065*WO 96/13517
- EP 0 661 985*WO 93/08817
- EP 0477231*WO 90/15878
- EP 0688338*WO 94/21675
- EP 0666869*WO 94/06828
- EP 0449973WO 90/06767
- EP 0469036WO 90/12587
- EP 0700301*WO 94/25034
- EP 0702696*WO 94/29349
- EP 0702692*WO 94/26773
- EP 0667908*WO 94/19470
- EP 0667786*WO 94/05311
- EP 0687182*WO 94/19011
- EP 0703783*WO 94/20127
- EP 0703786*WO 95/00168
- EP 0662079*WO 95/00534
- EP 0665888*WO 93/04174
- EP 0714440*WO 95/06728
- EP 0714441+WO 95/06121
- EP 0714442*WO 95/06122
- EP 0704457
- EP 0714444*WO 95/06124
- EO 0674710*WO 94/11509
- EP 0670901*WO 94/20622
- EP 0671946*WO 04/06470
- EP 0656010*WO 94/03487
- EP 0662 838*WO 94/07520
- EP 0359783WO 88/10120
- EP 0716696*WO 95/06727
- EP 0725824*WO 95/12677
- EP 0725825*WO 95/07354
- EP 0738281*WO 95/19375
- EP 0738322*WO 95/19435
- EP 0737205*WO 95/18148
- Monoclonale Antikörper und Assays
- EP 0506826WO 91/09059
- EP 0673389*WO 94/11404
- EP 0667902*WO 93/11237
- EP 0371036WO 88/09672
- EP 0684828*WO 94/18991
- EP 0695312*WO 94/00459
- EP 0436545WO 89/10754
- EP 0669836*WO 94/11026
- EP 0710293*WO 95/02703
- EP 0720624*WO 95/08577
- EP 0717848*WO 95/07466
- EP 0725838*WO 95/11998
- EP 0722489*WO 95/07348
- EP 0741748*WO 95/21868
- EP 0724634*W0 95/06723
- EP 0724652*WO 95/11317
- EP 0736088*WO 95/17502
- EP 0737251*WO 95/20045
- EP 0737250*WO 95/16038
- EP 0741515*WO 95/17085
- Chimerische Proteine, Drug Targeting, Proteinreinigung
- EP 0689599*WO 94/17193
- EP 0679094*WO 94/15644 Compounds for targeting.
- EP 0741788*WO 95/01671
- EP 0688335*WO 94/20525
- EP 0448707*WO 91/04316
- EP 0682705*WO 94/18325
- EP 0668353
- EP 0668354
- EP 0672143*WO 94/13808
- EP 0401384WO 90/06952
- EP 0733067*WO 95/01729
- Galenik
- EP 0730470*WO 95/13090
- EP 0674525*WO 94/14466
- EP 0674524*WO 94/14465
- EP 0278474
- EP 0554634
- EP 0702723*WO 94/24298
- EP 0478715WO 91/00289
- EP 0568594WO 92/12999
- EP 0707473*WO 94/28879
- EP 0710101*WO 94/12142
- EP 0710102*WO 95/03034
- EP 0714406*WO/ 95/06064
- EP 0731691*WO 96/10394
- EP 0732935*WO 95/17206
- Konjugierte Antikörper, Kopplungen
- EP 0702792WO 95/27902
- EP 0702793*WO 94/29724
- EP 0731917*WO 95/15498
- EP 0731916*WO 95/15496
Morphogen-enriched dietary composition.
Creative Biomolecules
Morphogen-induced liver regeneration.
Creative Biomolecules
Morphogen protein soluble complex and composition thereof.
Creative Biomolecule
Morphogen-induced periodontal tissue regeneration.
Creative Biomolecules
OP-3-induced morphogenesis.
Creative Biomolecules
Morphogen treatment of gastrointestinal ulcers.
Creative Biomolecules
A truncated keratinocyte growth factor (KGF) having increased biological activity.
Chiron
Inhibition of migration inhibitory factor in the treatment of diseases involving cytokine-mediated toxicity.
The Picower Institute for Medical Research
Immunologic enhancement with intermittent interleukin-2 therapy.
National Institute of Health, Bethesda, MD,US
Dorsal tissue affecting factor and compositions.
University of California
Cloning, expression and uses of Dorsaline-1.
Columbia University, New York, US
Compositions and methods for modifying the regulatory activity of TGF-g(b).
HSC Research Development Ltd
Inhibitors of cell regulatory factors and methods for preventing or reducing scarring.
La Jolla Cancer Research Foundation
Modified ciliary neurotrophic factors.
Regeneron Pharmaceuticals
Method of producing analgesia using neurotrophins.
Regeneron Pharmaceuticals
Vascular endothelial cell growth factor antagonists.
Genentech
Treatment of cachexia and inhibition of IL-6 activity.
Otsuka America Pharmaceutical
EP 0662837*WO 94/08606
Use of IL-10 to prevent or treat insulin-dependent diabetes mellitus.
Schering
Enhancement of xenograft tolerance and porcine cytokines thereof.
Biotransplant
Mutant interleukin 6 with improved biological activity over wild interleukin 6.
Istituto di Ricerche di Biologia Moleculare P. Angeletti
Recombinant human erythropoietin with altered biological activity.
New England Deaconess Hospital
TNF--g(a) ribozymes and degradation resistant mRNA derivatives linked to TNF--g(a) ribozymes.
Gene Shears
Method of neutralizing IL-1 using dsRNAs.
HEM Pharamceuticals
Receptor for Onkostatin M and leukemia inhibitory factor.
Immunex
Use of GM-CSF as a vaccine adjuvant.
Schering Corporation
Interleukin-2 stimulated T lymphocyte cell death for the treatment of autoimmune diseases, allergic disorders, and graft rejection
Department of Health and human services, Bethesda
Inhibition of migration inhibitory factor in the treatment of diseases involving cytokine mediated toxicity
Picower Institute for Medical Research
Purified mammalian FLT3 ligands and agonists and antagonists thereof
Schering Corp.
Mutated growth factor receptor as medicament and ist use for treating cancer
Max-Planck-Gesellschaft zur Förderung der Wissenschaften
Mammalian receptors for interleukin-10 (IL-10)
Schering
Interleukin-6 receptor antagonists
Cetus Oncology
Interleukin-3 (IL-3) multiple mutation polypeptides
G.D. Searle
Interferon regulatory factors 1 and 2 in the diagnosis of tumorigenicity
University of California
Compositions containing growth factors and antineoplastic agents
Alcon Laboratories
Use of growth hormone for increasement of concentration of GH, IGF-1 and IGFBP-3 in cerebrospinal fluid
Pharmacia
Assay systems using the CNTF signal transduction pathway
Regeneron
Methods and compositions for stimulating and inhibiting TGF-ß activity
The UAB Research Foundation
Neural regeneration using human bone morphogenetic proteins
Genetics Institute
DNA sequence coding for a BMP receptor
Procter & Gamble
Labeled chemotactic peptides to image focal sites of infection or inflammation.
Ortho Pharmaceutical
Hybrid Cytokines
Fred Hutchinson Cancer Research Center
Vertebrate embryonic pattern-inducing hedgehog-like proteins
Harvard College
Novel peptides derived from autoantigen for use in immunotherapy of autoimmune diseases.
Akzo Nobel
CD8 binding domain peptides.
Leland Stanford Junior University
Immunoactive peptides and antibodies and their use in anti-allergy treatment.
British Technology Group
T cell epitopes of ryegrass pollen allergen.
Immunologic Pharmaceutical Corporation
Peptides tolerizing T-cells and compositions thereof.
Washington University
Polypeptide-polymer conjugates active in wound healing.
La Jolla Cancer Research Foundation
Composition and treatment with biologically active peptides and antibiotic.
The Children's Hospital of Philadelphia
Peptides and compounds that bind to ELAM-1.
Affymax Technologies
Trifunctional antithrombin and antiplatelet peptides.
Merrel Pharmaceuticals, Cincinnati, US
Regulation of antigen presentation.
Antigen Express, Wilmington, US
Soluble T-cell receptor alpha chain and derivatives used as prophylactic and therapeutic agents for treating autoimmune diseases.
Hoechst Japan
Retro-, Inverso, and retro-inverso synthetic peptide analogues.
Deakin Research Ltd
Peptides for inducing cytotoxic T lymphocyte responses to hepatitis B virus.
The Scripps Research Institute
HLA-A2.1 binding peptides and their uses.
Cytel Corporation
Use of nona-and decapeptides in the preparation of a drug for the treatment of AIDS.
ASTA Medica
Alpha-helix mimetics and methods relating thereto.
University of Illinois, US
Ryegrass pollen allergen.
The University of Melbourne
T cell epitopes of ryegrass pollen allergen.
Immulogic Pharmaceutical Corporation
Recombinant Cladosporium herbarum allergens.
Biomay
Recombinant Alternaria Alternata allergens.
Biomay
Allergenic proteins of natural rubber latex, their production and use in assays.
Rubber Research Institute of Malaysia
Dampening of an immunodominant epitope of an antigen for use in plant, animal and human vaccines and immunotherapies.
National Institute of Health
Peptides and anti-sense peptides with broad neoplastic specificity.
Cancer Research Fund of Contra Costa
Polypeptide fragment capable of inducing neutralising antibodies against feline immuno-deficiency virus.
Akzo Nobel
Immunoreactive peptides from Epstein-Barr Virus.
Johnson and Johnson
New peptides, antibodies raised against peptides and means for blocking said antibodies, application as medicaments, pharmaceutical compositions and utilizing methods.
Neovacs
Method of treating rheumatoid arthritis with type II collagen.
Autoimmune Inc
Treatment of autoimmune diseases by oral administration of autoantigens.
Autoimmune Inc.
Use of myelin oligodendrocyte glycoprotein and peptide protions thereof in protocols related to autoimmune disease.
Immulogic Pharmaceutical Corp.
Immunodominant human T-cell epitopes of hepatitis C virus.
N.V. Innogenetics
Peptides that elicit neutralizing antibodies against genetically divergent HIV-1 strains.
Polymun Scientific Immunobiologische Forschung
Peptides and methods against psoriasis.
The Immune Response Corporation
T cell antigen receptor V region proteins and methods of preparation thereof.
T Cell Sciences, Inc.
T cell epitopes.
Chiron Mimotopes
Antibody antagonists of human interleukin-4.
Schering
Antibodies for GM-CSF receptor and uses thereof.
Dana Farber Cancer Institute
CDR grafted humanized chimeric T-cell antibodies.
The Wellcome Foundation, London, GB
Method of reducing tissue damage at an inflammatory site using a monoclonal antibody.
University of Michigan
Expansion of stem cells in long term bone marrow cultures by neutralizing of TGF--g(b).
Celtrix Pharmaceuticals
Immunoparticles bearing monoclonal anti-CD4 antibodies and utilisation thereof.
Laboratoires UPSA
Therapeutic methods using catalytic antibodies.
Igen
Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma.
Idec Pharmaceuticals
Lyophilized ligand-receptor complexes for assays and sensors.
US Drug Testing Inc.
Retargeting antibodies.
Medical Research Council London
EP 0721015*WO 95/06748
Monoclonal antibody that induces apoptosis.
Chugai Seiyaku Kabushiki Kaisha
Biotin-analog conjugated antibodies for positive cell selection and release.
Baxter International
Structured synthetic antigen libraries as diagnostics, vaccines and therapeutics.
United Biomedicals
Monoclonal antibodies that recognize FLK-2 receptors and the isolation of primitive hematopoietic stem cell populations.
Imclone Systems
Monoclonal antibodies specific to VEGF receptors and uses thereof.
Imclone Systems
Method of marking eukaryotic cells by use of a cell surface receptor as a marker.
Boehringer Mannheim
Synthetic human neutralizing monoclonal antibodies to human immunodeficiency virus.
Scripps Research Institute
Monoclonal antibodies to hepatitis E virus and methods for using same.
Abbott Laboratories
Antibodies to EGF receptor and their antitumor effect.
The Institute of Cancer Research: Royal Cancer Hospital
Humanized antibodies and uses thereof.
T Cell Sciences
Transgenic production of antibodies in milk.
Genzyme Transgenics Corporation
Chimeric L- and P-selectin by exchange of domains - uses thereof.
Dana Faber Cancer Institute
Imperial Cancer Research Technology, London, GB
Inducing tolerance with tolerogenic fusion proteins.
American National Red Cross
Purification of human interleukin-10.
Schering Corporation
Bacteria harboring expression vectors encoding human ciliary neurotrophic factor (h-CNTF), their use in the production of h-CNTF, antibodies to h-CNTF and the use of h-CNTF in mediacl treatment.
Max-Planck-Gesellschaft zur Förderung der Wissenschaften
TNF-alpha muteins and a process for preparing them.
N.N. Innogenetics
Cysteine added variants of EPO and chemical modifications thereof.
Genetics Institute
Cysteine added variants of G-CSF and chemical modifications thereof.
Genetics Institute
Lymphotoxin-beta, lymphotoxin-beta complexes, pharmaceutical preparations, and therapeutic uses thereof.
Biogen
Chemically modified granulocyte colony stimulating factor
Kirin-Amgen
Method of binding recognizing substances to liposomes
Baxter International
Improved interferon polymer conjugates
Enzon
Aqueous pharmaceutical preparations of G-CSF with a long shelf life
Boehringer Mannheim
Stable lyophylized pharmaceutical preparations of G-CSF
Boehringer Mannheim
Electrolytic transdermal delivery of polypeptides
Drug Delivery Sytsems
Stabilized pharmaceutical composition comprising non-glycosylated, reduced, recombinant human IL-2 and process to prepare it
ROUSSEL UCLAF
Biocompatible implant for the expression of a therapeutical compound
Institut Pasteur, Paris, France
Targeted liposomes and methods for liposome-protein coupling
The Liposome Company
Novel insulin analogs suited for transdermal delivery
Novo Nordisk
Oral pharmaceutical compositions comprising a protein or peptide, an antibody and polymeric beads
Biotechnology and Biological Sciences Research Council, Swindon
Improved method for manufacturing freeze dried dosages in a multilaminate blister pack
R.P. Scherer Ltd.
Stabilization of aerosolized proteins
Amgen
Refolding of polypeptides like recombinant insulin-like growth factor IGF-1
Genentech
Method of binding recognizing substances to liposomes
Baxter International
Lyophilized stem cell factor formulations
Amgen
Random detection of antigens with antibodies immobilized on soluble submicron particles
Dade International
Anti-CD3 antibody-aminodextran conjugates for induction of T-cell activation and proliferation
Coulter Corp.
Immunoassays employing generic anti-hapten antibodies and materials for use therein
Abbott
Ultrasensitive competitive immunoassays using optical waveguides
FCI-Fiberchem
